High-grade squamous intraepithelial lesion of the oral commissure (bowenoid papulosis). A case and review.

A) Verruca vulgaris B) Actinic keratosis C) Bowenoid papulosis D) Seborrheic keratosis E) Acanthoma High-grade squamous intraepithelial lesion of the oral commissure (bowenoid papulosis). Citation: Kupetsky EA, Charles CA, Mones J. High-grade squamous intraepithelial lesion of the oral commissure (bowenoid papulosis). A case and review. Copyright: ©2015 Kupetsky et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Figure 1. Scanning magnification of the lesion on the oral commis-sure. [Copyright: ©2015 Kupetsky et al.] Figure 2. Higher magnification of the oral lesion. [Copyright: ©2015 Kupetsky et al.] Figure 3. Higher magnification of the slightly verrucous lesion shows hyperplasia with full-thickness atypia of squamous epithelial cells, evidence of loss of polarity, nuclear crowding, nuclear pleomorphism and increased mitotic figures indicative of high-grade squamous in-traepithelial lesions. [Copyright: ©2015 Kupetsky et al.]